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Macrophage Inflammatory Protein 3 alpha, Recombinant, Human (MIP-3a, Exodus, LARC)
Macrophage Inflammatory Protein 3 alpha, Recombinant, Human (MIP-3a, Exodus, LARC)
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| Human Macrophage Inflammatory Protein-3 alpha, also known as LARC (Liver and Activiation Regulated Chemokine) or CCL20. This protein in strongly up regulated by inflammatory signals, and down regulated by the anti-inflammatory cytokine IL-10. H-MIP-3-alpha is a non-glycosylated polypeptide chain consisting of 70 amino acids and a molecular weight of 8.0kD. | | | Catalog # | M1202-60J | | Endotoxin | <0.01ng/ug or <0.1EU/ug as per LAL | | Biological Activity | Human MIP-3-alpha is a chemoattractant to human T cells working in a concentration range of 10.0-50.0ng/ml. | | Amino Acid Sequence | ASNFDCCLGY TDRILHPKFI VGFTRQLANE GCDINAIIFH TKKKLSVCAN PKQTWVKYIV RLLSKKVKNM | | Storage and Stability | Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O, aliquot and store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | Molecular Weight | 8.0 kD | | Source | Recombinant, human, E. coli | | Purity | 97% as determined by RP-HPLC and reducing and non-reducing SDS-PAGE. | | Form | Supplied as a lyophilized powder. Reconstitute with sterile dH2O PBS to 0.1-1mg/ml, which can be further diluted into other aqueous solutions. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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