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You are here:Home » Molecular Biology » Growth Factors-MIP » Macrophage Inflammatory Protein 3 beta, Recombinant, Human (MIP-3b, Exodus-3, ELC)

Macrophage Inflammatory Protein 3 beta, Recombinant, Human (MIP-3b, Exodus-3, ELC)

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Specifications

MIP-3 beta is a CC chemokine that is expressed in the thymus, lymph nodes and in activated bone marrow stromal cells and signals through the CCR7 receptor. MIP-3 beta is a chemoattractant for T and B lymphocytes and myeloid progenitor cells. Human MIP-3 beta is active on murine cells. Recombinant human MIP-3 beta is an 8.8kD protein containing 77 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.
Catalog #M1202-65
AA SequenceGTNDAEDCCL SVTQKPIPGY IVRNFHYLLI KDGCRVPAVV FTTLRGRQLC APPDQPWVER IIQRLQRTSA KMKRRSS
ReconstitutionReconstitute with sterile dH2O to 0.1-1.0mg/ml. This solution can then be diluted into other buffers and stored at 4°C for 1 week or stored at -20°C for future use.
Biological ActivityDetermined by its ability to chemoattract human T cells using a concentration of 10-50ng/ml.
Storage and StabilityLyophilized powder may be stored at 4°C for short-term only. Reconstitute to nominal volume by adding sterile dH2O, aliquot and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight8.8kD
SourceE. coli
Purity98% by SDS-PAGE and HPLC analyses. Endotoxin: 0.1ng/ug (1EU/ug)
ConcentrationAs reported
FormSupplied as a lyophilized powder from a sterile filtered solution, lyophilized without additives. Reconstitute with sterile dH2O to 0.1-1.0mg/ml. This solution can then be diluted into other buffers.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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