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You are here:Home » Molecular Biology » MB-Growth Factors-MCP » Monocyte Chemotactic Protein-1 (MCP-1), Recombinant, Human

Monocyte Chemotactic Protein-1 (MCP-1), Recombinant, Human


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Recombinant MCP-1 comprises a 76 amino acid fragment (24-99) corresponding to the mature MCP-1 protein and is expressed in E. coli with an amino-terminal hexahistidine tag.
Catalog #M1203-02T
MCP-1 is a member of the CC subgroup of the chemokine superfamily. It is produced by a variety of cell types including monocytes, lymphocytes, endothelial cells and fibroblasts after stimulation by any inflammatory mediator. MCP-1 acts as a potent chemoattractant and is thought to play an important role in the inflammatory response of blood monocytes, tissue macrophages and natural killer cells. Its expression has been documented in disorders characterized by mononuclear cell infiltrates, suggesting that it may contribute to the inflammatory component of diseases such as atherosclerosis, multiple sclerosis, or rheumatoid arthritis.
ApplicationsSuitable for use in ELISA Other applications not tested.
Recommended Dilution:
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
SourceHuman, Recombinant, E. coli
PurityPurified. 95% by SDS-PAGE.
ConcentrationAs reported
FormSupplied as a liquid.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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