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You are here:Home » Molecular Biology » Growth Factors-MCP » MCP-1, Recombinant, Human (C-C Motif Chemokine 2, HC11, Monocyte Chemoattractant Protein 1, Monocyte Chemotactic and Activating Factor, MCAF, Monocyte Chemotactic Protein 1, Monocyte Secretory Protein JE, Small-inducible Cytokine A2, CCL2, SCYA2)

MCP-1, Recombinant, Human (C-C Motif Chemokine 2, HC11, Monocyte Chemoattractant Protein
1, Monocyte Chemotactic and Activating Factor, MCAF, Monocyte Chemotactic Protein 1,
Monocyte Secretory Protein JE, Small-inducible Cytokine A2, CCL2, SCYA2)

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Specifications

MCP-1 is a member of the CC subgroup of the chemokine superfamily. It is produced by a variety of cell types including monocytes, lymphocytes, endothelial cells and fibroblasts after stimulation by any inflammatory mediator. MCP-1 acts as a potent chemoattractant and is thought to play an important role in the inflammatory response of blood monocytes, tissue macrophages and natural killer cells. Its expression has been documented in disorders characterized by mononuclear cell infiltrates, suggesting that it may contribute to the inflammatory component of diseases such as atherosclerosis, multiple sclerosis, or rheumatoid arthritis.
Catalog #M1203-04Q
SourceRecombinant corresponding to aa24-99 from mature human MCP-1, fused to 6x His-tag at N-terminal, expressed in E. coli.
ApplicationsSuitable for use in Western Blot as a control. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
SourceE. coli
PurityPurified (SDS-PAGE)
ConcentrationAs reported
FormSupplied as a liquid in 25mM Tris-HCl, pH6.8, 50mM DTT, 1% SDS, 0.1% Bromophenol Blue, 2.5% glycerol.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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