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You are here:Home » Antibodies » Abs to RNA Processing » Anti -MAEL, CT (Protein Maelstrom Homolog, CT128, FLJ14904, RP11-102C16.1)

Anti -MAEL, CT (Protein Maelstrom Homolog, CT128, FLJ14904, RP11-102C16.1)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B
MAEL plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. It acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Its association with piP-bodies suggests a participation in the secondary piRNAs metabolic process. Required for localization of germ-cell factors to the meiotic nuage (By similarity).
Catalog #M1727-50
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:1,000
Western Blot: 1:100-1:500
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
CAS Numbern/a
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~0.25mg/ml
FormSupplied as a liquid in PBS, 0.09% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide selected from the C-terminal region of human MAEL (KLH).
SpecificityRecognizes human MAEL.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesMaelstrom Homolog (Drosophila)


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