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You are here:Home » Antibodies » Abs to Transcription Factors, Zinc (Ring) Finger » Anti -Makorin (HGNC:7112, Makorin Ring Finger Protein 1, MKRN1, RING Finger Protein 61, RNF61)

Anti -Makorin (HGNC:7112, Makorin Ring Finger Protein 1, MKRN1, RING Finger Protein 61,
RNF61)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Serum B IH
MKRN1 (Makorin ring finger protein 1) is a a ubiquitously expressed novel RING zinc finger protein, a member of the Makorin family of proteins. The MKRN gene family encodes putative ribonucleoproteins with a distinctive array of zinc finger motifs, including two to four C(3)H zinc fingers, an unusual Cys/His arrangement that may represent a novel zinc finger structure, and a highly conserved RING zinc finger. So far, nine MKRN family loci have been found distributed throughout the human genome. The MKRN1 gene is highly transcribed in mammals. The MKRN1 protein has been shown to act as an E3 ubiquitin ligase and may represent a nuclear protein with multiple nuclear functions, including the regulation of RNA polymerase II catalyzed transcription.
Catalog #M2112-25C
ApplicationsSuitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 1:500-1:2000
Immunohistochemistry: 1:100-1:1000
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at 4°C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20°C. Reconstituted product is stable for 3 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
HostRabbit
SourceHuman
ConcentrationNot Determined.
FormSupplied as a lyophilized powder in PBS.
PuritySerum
ImmunogenSynthetic peptide corresponding to Nter domain of human MKRN1 protein.
SpecificityRecognizes human MKRN1 at ~53kD. Species Crossreactivity: mouse and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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