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You are here:Home » Antibodies » Abs to Syntaxin, Synaptotagmin, Synaptophysin » Anti -STXBP1, ID (Syntaxin-binding Protein 1, Protein Unc-18 Homolog, Unc-18-1, Protein Unc-18 Homolog A, Unc-18A, N-Sec1, p67, UNC18A)

Anti -STXBP1, ID (Syntaxin-binding Protein 1, Protein Unc-18 Homolog, Unc-18-1, Protein
Unc-18 Homolog A, Unc-18A, N-Sec1, p67, UNC18A)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E IH IF
Catalog #M2197-03J
STXBP1 may participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. The protein is essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 11 ratio. It can interact with syntaxins 1, 2, and 3 but not syntaxin 4 and may play a role in determining the specificity of intracellular fusion reactions.
ApplicationsSuitable for use in ELISA, Immunofluorescence and Immunohistochemistry. Other applications not tested.
Recommended DilutionELISA: 1:40,000
Immunofluorescence: 1:100-1:500
Immunohistochemistry (Formalin fixed paraffin embedded): 10ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS (without Mg2+, Ca2+), pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to human MUNC-18a.
SpecificityRecognizes human STXBP1. Species sequence homology: mouse and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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