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Anti -Mannan Binding Protein (MBP, Mannose Binding Protein, Mannan Binding Lectin, MBL)
Anti -Mannan Binding Protein (MBP, Mannose Binding Protein, Mannan Binding Lectin, MBL)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Ascites |
E B |
|
| This gene encodes the soluble mannose-binding lectin or mannose-binding protein found in serum. The protein encoded belongs to the collectin family and is an important element in the innate immune system. The protein recognizes mannose and N-acetylglucosamine on many microorganisms, and is capable of activating the classical complement pathway. Deficiencies of this gene have been associated with susceptibility to autoimmune and infectious diseases. | | | Catalog # | M2245 | | Applications | Suitable for use in Western Blot and ELISA. Other applications not tested. | | Recommended Dilutions | Western Blot: 1:5000-1:10,000. Reacts with the ~30kD human MBL protein. Suggested blocking and dilution buffer is TBST with 0.05% Tween-20, 5% skim milk. Suggested incubation time is one hour at RT. | | ELISA (Direct and indirect): 1:5000-1:10,000 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | 3H405 | | Host | Mouse | | Source | Human | | Concentration | Not Determined | | Form | Supplied as a liquid in PBS, pH 7.4. | | Purity | Ascites | | Immunogen | Natural MBL from human plasma | | Specificity | Recognizes both natural and recombinant human Mannan (Mannose)-Binding Lectin (MBL) protein. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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