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You are here:Home » Antibodies » Abs to Lectins » Anti -MBL-C (Mannose-binding Lectin C, MBP-C, Collectin-1, MBP1, Mannan-binding Protein, MBL2, COLEC1)

Anti -MBL-C (Mannose-binding Lectin C, MBP-C, Collectin-1, MBP1, Mannan-binding Protein,
MBL2, COLEC1)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B
Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. May bind DNA.
Catalog #M2250-01G
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:4000
Western Blot: 1-3ug/ml, observed in human heart and kdney lysates on ~26kD bands
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to STSHLAVCEFPI, from human MBL2, at C-terminal (NP_000233.1).
SpecificityRecognizes human MBL2.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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