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You are here:Home » Antibodies » Abs to Golgi Proteins » Anti -Mannose 6 Phosphate Receptor, Cation-independent (Cation-independent Mannose-6-phosphate Receptor, CI Man-6-P Receptor, CI-MPR, M6PR, 300kD Mannose 6-phosphate Receptor, MPR 300, Insulin-like Growth Factor 2 Receptor, Insulin-like Growth Factor II Recepto

Anti -Mannose 6 Phosphate Receptor, Cation-independent (Cation-independent
Mannose-6-phosphate Receptor, CI Man-6-P Receptor, CI-MPR, M6PR, 300kD Mannose 6-phosphate
Receptor, MPR 300, Insulin-like Growth Factor 2 Receptor, Insulin-like Growth Factor II
Recepto

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E
Insulin-like Growth Factor 2 receptor (IGF-II R), also known as cation-independent mannose-6 phosphate receptor (CI-MPR), is a 300kD, 2264aa type I transmembrane glycoprotein of the P-type lectin family. The extracellular region contains 15 repeats that mediate homodimer formation and multifunctional binding of IGF-II and many other proteins that do and do not contain mannose-6 phosphates. IGF-II R generally regulates endocytosis and lysosomal/endosomal trafficking. Human IGF-II R shares 85% aa identity with mouse and cow IGF-II R within the extracellular region used as an immunogen.
Catalog #M2255-17B
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionELISA:2-8ug/ml
Optimal dilutions to be determined by the researcher.
HybridomaFusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, NS0-derived, recombinant human IGF-II R.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG2B
Clone No10K74
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a lyophilized powder from a 0.2um filtered solution in PBS, 5% trehalose. Reconstitute with sterile PBS.
PurityPurified by Protein G affinity chromatography.
ImmunogenPurified, NS0-derived, recombinant human IGF-II R (aa1510-2108; Accession #P11717).
SpecificityRecognizes human IGF-II R. Species sequence homology: mouse, cow (85%).
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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