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You are here:Home » Antibodies » Abs to Microtubule-associated Proteins » Anti -MAP1LC3A (Microtubule Associated Protein 1 Light Chain 3 alpha, MAP1 Light Chain 3A, APG8, Autophagy Related Protein LC3A, Autophagy Related Ubiquitin-like Modifier LC3A, LC3A, MAP1 Light Chain 3 Like Protein 1, Microtubule Associated Proteins 1A/1B Light

Anti -MAP1LC3A (Microtubule Associated Protein 1 Light Chain 3 alpha, MAP1 Light Chain 3A,
APG8, Autophagy Related Protein LC3A, Autophagy Related Ubiquitin-like Modifier LC3A,
LC3A, MAP1 Light Chain 3 Like Protein 1, Microtubule Associated Proteins 1A/1B Light

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified IH
MAP1A and MAP1B are microtubule-associated proteins made up of a heavy chain and multiple light chain components. One such light chain component associated with these proteins is APG8. APG8, an ~16kD mammalian homolog of yeast Atg8, is a cytoplasmic protein that plays an essential role in the process and regulation of autophagy. APG8 is an evolutionarily conserved protein that belongs to LC3 family. APG8 interacts with various proteins in the cytoplasm including mammalian homologues of Atg4, Atg7, Atg3 and Atg12 and gets modified into LC3-I and LC3-II respectively. Both of these forms are suggested to be involved in the formation and intracellular trafficking of autophagosomes in mammalian cells.
Catalog #M2346-15K
ApplicationsSuitable for use in Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (Formalin fixed paraffin embedded): 3.75-7.5ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline buffer, pH 7.3, 0.5% BSA, 0.02% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to C-DIYEQEKDED from aa97-106 of human MAP1LC3A (NP_115903.1).
SpecificityRecognizes human MAP1ALC3.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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