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You are here:Home » Antibodies » Abs to Microtubule-associated Proteins » Anti -Microtubule-associated Protein 2 (MAP2, MAP-2)

Anti -Microtubule-associated Protein 2 (MAP2, MAP-2)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B IP IH IC
MAP2 is a type II microtubule associated protein (MAP). It is located predominately in dendrites where it accelerates tubulin polymerization, cross-links microtubule fibers into stable bundles, and connects microtubule filaments to intermediate filaments. Alternative splicing of MAP2 mRNA gives rise to at least three different isoforms including; MAP2a (280kD), MAP2b (200kD), and MAP2c (70kD). The MAP2c isoform is expressed in embryos, whereas the MAP2a and MAP2b isoforms are expressed in adult tissues. MAP2 is the somatodentritic MAP of neurons, but it also is expressed to a lesser extent in glia.
Catalog #M2350-01F2
ApplicationsSuitable for use in ELISA, Western Blot, Immunoprecipitation, Immunohistochemistry and Immunocytochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (Formalin fixed paraffin embedded): 10ug/ml
Immunohistochemistry: Frozen
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1
Clone NoMT-08
HostMouse
SourceBovine
Concentration~1mg/ml
FormSupplied as a liquid in PBS, 15mM sodium azide, pH 7.4.
PurityPurified by Protein A affinity chromatography.
ImmunogenMicrotubule protein (bovine brain) enriched for kinesin
SpecificityRecognizes bovine MAP2. Species sequence homology: Mouse, porcine, human.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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