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You are here:Home » Antibodies » Abs to Protein Kinase Substrates » Anti -MARCKS, phosphorylated (Ser152/156) (Myristolated Alanine Rich C Kinase Substrate, Myristoylated Alanine Rich Protein Kinase C Substrate, MACS, MARCS, 80K-L Protein, 81kD Protein Light Chain, MGC52672, Phosphomyristin, PKCSL, PRKCSL, Protein Kinase C Subs

Anti -MARCKS, phosphorylated (Ser152/156) (Myristolated Alanine Rich C Kinase Substrate,
Myristoylated Alanine Rich Protein Kinase C Substrate, MACS, MARCS, 80K-L Protein, 81kD
Protein Light Chain, MGC52672, Phosphomyristin, PKCSL, PRKCSL, Protein Kinase C Subs

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B
Myristoylated alanine-rich protein kinase C substrate (MARCKS) is a major PKC substrate that is distributed in various cell types. MARCKS has been implicated in cell motility, cell adhesion, phagocytosis, membrane traffic and mitogenesis (1). PKC phosphorylates serines 152, 156 and 163 of MARCKS (2), which regulates MARCKS’s calcium/calmodulin binding activity and filamentous (F)-actin cross-linking activity (3,4). In addition, phosphorylation by PKC results in translocation of MARCKS from membrane to cytoplasm (5).
Catalog #M2375-05
Recommended Dilution Western Blotting: 1:1000
Optimal dilutions to be determined by the researcher.
Storage and Stability May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
HostRabbit
SourceRat
ConcentrationNot determined
FormSupplied as liquid in 10mM HEPES, pH 7.5, 150mM sodium chloride, 0.1mg/ml BSA, 50% glycerol. No preservative added.
PurityPurified by Protein A affinity chromatography.
ImmunogenSynthetic phosphopeptide (KLH coupled) corresponding to residues surrounding Ser152/156 of rat MARCKS.
SpecificityDetects endogenous levels of Ser152/156 phosphorylated MARCKS. Species Crossreactivity: Human and mouse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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