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You are here:Home » Antibodies » Abs to Protein Kinase Substrates » Anti -MARCKS, CT (Myristoylated Alanine-rich C-kinase Substrate, Protein Kinase C Substrate, 80kD Protein, Light Chain, PKCSL, 80K-L Protein, MACS, PRKCSL)

Anti -MARCKS, CT (Myristoylated Alanine-rich C-kinase Substrate, Protein Kinase C
Substrate, 80kD Protein, Light Chain, PKCSL, 80K-L Protein, MACS, PRKCSL)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B
MARCKS is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis.
Catalog #M2375-05J
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:1,000
Western Blot: 1:50-1:100
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, 0.09% sodium azide.
PurityPurified by Protein G affinity chromatography.
ImmunogenSynthetic peptide selected from the C-terminal region of human MARCKS (KLH).
SpecificityRecognizes human MARCKS.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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