Login

Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Antibodies » Abs to Cancer Markers » Anti -MART-1, multiple clones (Melanoma Antigen Recognized by T-cells 1, Melan-A)

Anti -MART-1, multiple clones (Melanoma Antigen Recognized by T-cells 1, Melan-A)

Pricing

  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.

Specifications

Clone Host Grade Applications
Monoclonal Mouse Purified IH
Melanoma Antigen Recognized by T cells (MART-1), a widely shared melanoma epitope, is a 118aa protein with an approximate molecular weight of 18kD. MART-1 is recognized by HLA-A2-restricted autologous and allogeneic tumor-infiltrating lymphocytes from patients with established melanoma. MART-1 is expressed by a large proportion of melanomas and also in human and murine melanocyte lineage cells derived from skin, uvea, and retina. MART-1 is not
expressed in other normal tissues, including T cells, B cells, kidney epithelial cells, and fibroblasts. The antigen is not detectable in non-melanoma malignancies, including neoplasms of colon, breast, brain, kidney, lung and bone.
Catalog #M2410-13C
ApplicationsSuitable for use in Immunohistochemistry. Other applications have not been tested.
Recommended DilutionsImmunohistochemistry: Frozen and formalin-fixed, paraffin embedded tissue sections. Requires HEIR with Citrate Buffer, pH 6.0
Optimal dilutions to be determined by the researcher.
Positive ControlMelanoma
Expected Staining PatternCytoplasmic
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1+IgG2b+IgG2b
Clone No6A118
HostMouse
Concentration~0.01mg/ml
FormSupplied as a liquid in PBS, pH 7.4, 1% BSA, 0.1% sodium azide.
PurityPurified
ImmunogenHuman MART-1 fusion protein.
SpecificityRecognizes human MART-1 (Melan-A).
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


External Links