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You are here:Home » Antibodies » Antibodies-Cancer Markers » Anti -MART-1, multiple clones (Melanoma Antigen Recognized by T-cells 1, Melan-A)

Anti -MART-1, multiple clones (Melanoma Antigen Recognized by T-cells 1, Melan-A)


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Clone Host Grade Applications
Monoclonal Mouse Purified IH
Melanoma Antigen Recognized by T cells (MART-1), a widely shared melanoma epitope, is a 118aa protein with an approximate molecular weight of 18kD. MART-1 is recognized by HLA-A2-restricted autologous and allogeneic tumor-infiltrating lymphocytes from patients with established melanoma. MART-1 is expressed by a large proportion of melanomas and also in human and murine melanocyte lineage cells derived from skin, uvea, and retina. MART-1 is not
expressed in other normal tissues, including T cells, B cells, kidney epithelial cells, and fibroblasts. The antigen is not detectable in non-melanoma malignancies, including neoplasms of colon, breast, brain, kidney, lung and bone.
Catalog #M2410-13C
ApplicationsSuitable for use in Immunohistochemistry. Other applications have not been tested.
Recommended DilutionsImmunohistochemistry: Frozen and formalin-fixed, paraffin embedded tissue sections. Requires HEIR with Citrate Buffer, pH 6.0
Optimal dilutions to be determined by the researcher.
Positive ControlMelanoma
Expected Staining PatternCytoplasmic
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
Clone No6A118
FormSupplied as a liquid in PBS, pH 7.4, 1% BSA, 0.1% sodium azide.
ImmunogenHuman MART-1 fusion protein.
SpecificityRecognizes human MART-1 (Melan-A).
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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