You are here:Home
»
Molecular Biology
»
MB-Protein Kinase Inhibitors
»
Masitinib, Free Base (4-[(4-methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-thiazolyl]amino]phenyl]-benzamide, AB-1010)
Masitinib, Free Base
(4-[(4-methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-thiazolyl]amino]phen
yl]-benzamide, AB-1010)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Masitinib mesylate (AB1010) is a protein tyrosine kinase inhibitor. In vitro it has greater activity and selectivity than imatinib mesylate against the wild-type c-Kit receptor and the mutated form in the juxtamembrane region. It also inhibits the PDGF and FGFR3 receptors. | | | Catalog # | M2412-27 | | Solubility | Soluble in DMSO at 200mg/ml; very poorly soluble in ethanol or water; maximum solubility in plain water is estimated to be about 10-20uM; buffers, serum, or other additives may increase or decrease the aqueous solubility. | | Storage and Stability | May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. | | CAS Number | 790299-79-5 | | Molecular Formula | C28H30N6OS | | Molecular Weight | 498.64 | | Purity | ~99% | | Form | Supplied as an off-white to pale yellow powder. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
External Links
|
