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You are here:Home » Molecular Biology » MB-Protein Kinase Inhibitors » Masitinib, Free Base (4-[(4-methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-thiazolyl]amino]phenyl]-benzamide, AB-1010)

Masitinib, Free Base
yl]-benzamide, AB-1010)


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Masitinib mesylate (AB1010) is a protein tyrosine kinase inhibitor. In vitro it has greater activity and selectivity than imatinib mesylate against the wild-type c-Kit receptor and the mutated form in the juxtamembrane region. It also inhibits the PDGF and FGFR3 receptors.
Catalog #M2412-27
SolubilitySoluble in DMSO at 200mg/ml; very poorly soluble in ethanol or water; maximum solubility in plain water is estimated to be about 10-20uM; buffers, serum, or other additives may increase or decrease the aqueous solubility.
Storage and StabilityMay be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
CAS Number790299-79-5
Molecular FormulaC28H30N6OS
Molecular Weight498.64
FormSupplied as an off-white to pale yellow powder.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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