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Anti -Maspin (Mammary-specific Serpin, SERPINB5, Protease inhibitor 5)
Anti -Maspin (Mammary-specific Serpin, SERPINB5, Protease inhibitor 5)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Supernatant |
E IH |
|
| Maspin or mammary-specific serpin is a tumor suppressor protein of serine proteinase inhibitor family. Its transcription is regulated in combinatorial fashion by Ets, p53 and AP-1. It is present in normal breast and prostatic epithelial cells but downregulated in the respective carcinomas. The extent of downregulation correlates with the progression of the carcinoma and may help in prognosis. | | | Catalog # | M2412-50 | | Applications | Suitable for use in ELISA and Immunohistochemistry. Other applications not tested. | | Recommended Dilutions | Immunohistochemistry (Formalin/paraffin): 1:12.5-1:25 for 20 minutes at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 1mM EDTA, pH 8.0, for 10-20 minutes followed by cooling at RT for 20 minutes. | | Optimal dilutions to be determined by the researcher. | | Positive Control | Prostate | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG2a,k | | Clone No | 5G153 | | Host | Mouse | | Source | Human | | Concentration | Not Determined | | Form | Supplied as a liquid, 0.09% sodium azide. | | Purity | Supernatant | | Immunogen | Recombinant protein corresponding to N-terminal region of human Maspin. Cellular Localization | | Specificity | Recognizes human Maspin. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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