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You are here:Home » Antibodies » Abs to Matrix Metalloproteinases » Anti -Matrix Metalloproteinase 1 (Matrix Metallopeptidase 1 (Interstitial Collagenase), Matrix Metalloproteinase-1, MMP1, MMP-1, CLG, CLGN, Fibroblast Collagenase, Interstitial Collagenase)

Anti -Matrix Metalloproteinase 1 (Matrix Metallopeptidase 1 (Interstitial Collagenase),
Matrix Metalloproteinase-1, MMP1, MMP-1, CLG, CLGN, Fibroblast Collagenase, Interstitial
Collagenase)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Serum IH
MMP-1 is a collagenase belonging to the matrix metalloproteinase (MMP) family. The matrix metalloproteinase (MMP) family consists of at least 25 zinc-dependent proteases that degrade multiple components of the extracellular matrix (ECM) and participate in connective tissue remodeling events. MMP-1 is widely distributed among endothelial, epithelial, and mesenchymal cells. It mainly digests interstitial collagens type I and III and also cleaves collagens of types VII and X. The gene localizes to chromosome 11q22.3. It degrades extracellular matrix and thereby promotes tumor invasion and progression.
Catalog #M2420-03W
ApplicationsSuitable for use in Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (paraffin): 1:25-1:50
Optimal dilutions to be determined by the researcher.
Positive ControlPlacenta
Cellular Localization
Cytoplasmic
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid in 0.05% sodium azide.
PuritySerum
ImmunogenSynthetic peptide from the middle region of the human MMP-1.
SpecificityRecognizes human MMP-1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesEC=3.4.24.7


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