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Abs to Matrix Metalloproteinases
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Anti -Matrix Metalloproteinase 1 (Matrix Metallopeptidase 1 (Interstitial Collagenase), Matrix Metalloproteinase-1, MMP1, MMP-1, CLG, CLGN, Fibroblast Collagenase, Interstitial Collagenase)
Anti -Matrix Metalloproteinase 1 (Matrix Metallopeptidase 1 (Interstitial Collagenase),
Matrix Metalloproteinase-1, MMP1, MMP-1, CLG, CLGN, Fibroblast Collagenase, Interstitial
Collagenase)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Serum |
IH |
|
| MMP-1 is a collagenase belonging to the matrix metalloproteinase (MMP) family. The matrix metalloproteinase (MMP) family consists of at least 25 zinc-dependent proteases that degrade multiple components of the extracellular matrix (ECM) and participate in connective tissue remodeling events. MMP-1 is widely distributed among endothelial, epithelial, and mesenchymal cells. It mainly digests interstitial collagens type I and III and also cleaves collagens of types VII and X. The gene localizes to chromosome 11q22.3. It degrades extracellular matrix and thereby promotes tumor invasion and progression. | | | Catalog # | M2420-03W | | Applications | Suitable for use in Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Immunohistochemistry (paraffin): 1:25-1:50 | | Optimal dilutions to be determined by the researcher. | | Positive Control | Placenta | | Cellular Localization | | | Cytoplasmic | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | Not determined | | Form | Supplied as a liquid in 0.05% sodium azide. | | Purity | Serum | | Immunogen | Synthetic peptide from the middle region of the human MMP-1. | | Specificity | Recognizes human MMP-1. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | EC=3.4.24.7 |
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