Anti -Matrix Metalloproteinase 1 (MMP-1, Interstitial Collagenase-1)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Purified |
E B IH |
|
| Matrix metalloproteinases (MMPs) are a family of at least 20 structurally related, zinc-containing enzymes that have the ability to breakdown connective tissue. MMP-1 is also known as collagenase, fibroblast collagenase and interstitial collagenase. MMP-1 has shown substrate specificity to collagens I, II, III, VII. VIII and X, aggrecan, versican, tenascin, casein, gelatin, alpha1-antitrypsin, myelin basic protein, L-selectin, pro-TNF, IL-1beta, pro-MMP-2 and pro-MMP-9 directly and indirectly by activating other MMPs. | | | Catalog # | M2420-05G | | Applications | Suitable for use in Western Blot, ELISA and Immunohistochemistry. Other applications have not been tested. | | Recommended Dilutions | ELISA: 1:3000-1:8000 | | Immunohistochemistry: 2ug/ml on frozen and paraffin embedded sections. | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG2b | | Clone No | 5K161 | | Host | Mouse | | Source | Human | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in 100mM borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added. | | Purity | Purified | | Immunogen | Recombinant Matrix Metalloproteinase 1 (MMP-1). | | Specificity | Recognizes human MMP-1. Does not crossreact with human MMP-2, MMP-3 or MMP-9. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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