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You are here:Home » Antibodies » Abs to Matrix Metalloproteinases » Anti -Matrix Metalloproteinase 1 (MMP-1, Interstitial Collagenase-1)

Anti -Matrix Metalloproteinase 1 (MMP-1, Interstitial Collagenase-1)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Purified E B IH
Matrix metalloproteinases (MMPs) are a family of at least 20 structurally related, zinc-containing enzymes that have the ability to breakdown connective tissue. MMP-1 is also known as collagenase, fibroblast collagenase and interstitial collagenase. MMP-1 has shown substrate specificity to collagens I, II, III, VII. VIII and X, aggrecan, versican, tenascin, casein, gelatin, alpha1-antitrypsin, myelin basic protein, L-selectin, pro-TNF, IL-1beta, pro-MMP-2 and pro-MMP-9 directly and indirectly by activating other MMPs.
Catalog #M2420-05G
ApplicationsSuitable for use in Western Blot, ELISA and Immunohistochemistry. Other applications have not been tested.
Recommended DilutionsELISA: 1:3000-1:8000
Immunohistochemistry: 2ug/ml on frozen and paraffin embedded sections.
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. 
Clone TypeMonoclonal
IsotypeIgG2b
Clone No5K161
HostMouse
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in 100mM borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added.
PurityPurified
ImmunogenRecombinant Matrix Metalloproteinase 1 (MMP-1).
SpecificityRecognizes human MMP-1. Does not crossreact with human MMP-2, MMP-3 or MMP-9.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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