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You are here:Home » Antibodies » Antibodies-Matrix Metalloproteinases » Anti -Matrix Metalloproteinase 1 (MMP-1, Interstitial Collagenase-1)

Anti -Matrix Metalloproteinase 1 (MMP-1, Interstitial Collagenase-1)


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Clone Host Grade Applications
Monoclonal Mouse Purified E B IH
Matrix metalloproteinases (MMPs) are a family of at least 20 structurally related, zinc-containing enzymes that have the ability to breakdown connective tissue. MMP-1 is also known as collagenase, fibroblast collagenase and interstitial collagenase. MMP-1 has shown substrate specificity to collagens I, II, III, VII. VIII and X, aggrecan, versican, tenascin, casein, gelatin, alpha1-antitrypsin, myelin basic protein, L-selectin, pro-TNF, IL-1beta, pro-MMP-2 and pro-MMP-9 directly and indirectly by activating other MMPs.
Catalog #M2420-05G
ApplicationsSuitable for use in Western Blot, ELISA and Immunohistochemistry. Other applications have not been tested.
Recommended DilutionsELISA: 1:3000-1:8000
Immunohistochemistry: 2ug/ml on frozen and paraffin embedded sections.
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. 
Clone TypeMonoclonal
Clone No5K161
FormSupplied as a liquid in 100mM borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added.
ImmunogenRecombinant Matrix Metalloproteinase 1 (MMP-1).
SpecificityRecognizes human MMP-1. Does not crossreact with human MMP-2, MMP-3 or MMP-9.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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