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You are here:Home » Antibodies » Abs to Matrix Metalloproteinases » Anti -Matrix Metalloproteinase 1 (MMP-1, Fibroblast/Interstital Collagenase-1)

Anti -Matrix Metalloproteinase 1 (MMP-1, Fibroblast/Interstital Collagenase-1)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Purified E B IH
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes a secreted enzyme which breaks down the interstitial collagens, types I, II, and III. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.
Catalog #M2420-13
ApplicationsSuitable for use in Immunohistochemistry, Western Blot and ELISA. Other applications not tested.
Recommended DilutionImmunohistochemistry: PLP fixed paraffin-embedded tissues required for best results.
Western Blot: 1ug/ml
Optimal dilution determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2a,k
Clone No2Q519
HostMouse
SourceHuman
Concentration~2mg/ml
FormSupplied as a liquid in PBS, pH 7.0, 2% BSA (protease free).
PurityPurified
ImmunogenSynthetic peptide containing aa332-350 of human MMP-1.
SpecificityRecognizes the precursor and active forms of human MMP-1. Does not react with human MMP-2, 3, 8, 9, 13 and bovine MMP-1
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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