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You are here:Home » Antibodies » Abs to Matrix Metalloproteinases » Anti -Matrix Metalloproteinase 1 (MMP-1, Fibroblast/Interstital Collagenase-1)

Anti -Matrix Metalloproteinase 1 (MMP-1, Fibroblast/Interstital Collagenase-1)

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Specifications

Clone Host Grade Applications
Monoclonal Rabbit Supernatant B IP IH IC FC
Human interstitial collagenase matrix metalloproteinase-1 (MMP-1) is synthesized and secreted by many cells, and plays an important role in a wide variety of pathophysiological degradation processes of extracellular matrices. The enzyme is secreted in a precursor form (pro-MMP-1) that is subsequently converted to active species, and the activity is regulated by the specific tissue inhibitors of metalloproteinases (TIMPs).
Catalog #M2420-15B
ApplicationsSuitable for use in Flow Cytometry, Western Blot, Immunoprecipitation, Immunohistochemistry, Immunocytochemistry. Other applications not tested.
Recommended DilutionFlow Cytometry: 1:20
Western Blot: 1:1,000
Immunohistochemistry (paraffin): 1:50-100
Immunocytochemistry: 1:100-250
Immunoprecipitation: 1:30
Optimal dilutions to be determined by the researcher.
Positive ControlSKBr-3 cell lysates
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG
Clone No9i45
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid in Tris-Glycine, pH 7.4, 0.15M sodium chloride, 0.05% BSA, 0.01% sodium azide, 40% glycerol.
PuritySupernatant
ImmunogenSynthetic peptide corresponding to residues on human MMP-1. Cellular Localization: Secreted extracellular space extracellular matrix.
SpecificityRecognizes human MMP-1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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