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Anti -Matrix Metalloproteinase 1 (MMP-1, Fibroblast/Interstital Collagenase-1)
Anti -Matrix Metalloproteinase 1 (MMP-1, Fibroblast/Interstital Collagenase-1)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Rabbit |
Supernatant |
B IP IH IC FC |
|
| Human interstitial collagenase matrix metalloproteinase-1 (MMP-1) is synthesized and secreted by many cells, and plays an important role in a wide variety of pathophysiological degradation processes of extracellular matrices. The enzyme is secreted in a precursor form (pro-MMP-1) that is subsequently converted to active species, and the activity is regulated by the specific tissue inhibitors of metalloproteinases (TIMPs). | | | Catalog # | M2420-15B | | Applications | Suitable for use in Flow Cytometry, Western Blot, Immunoprecipitation, Immunohistochemistry, Immunocytochemistry. Other applications not tested. | | Recommended Dilution | Flow Cytometry: 1:20 | | Western Blot: 1:1,000 | | Immunohistochemistry (paraffin): 1:50-100 | | Immunocytochemistry: 1:100-250 | | Immunoprecipitation: 1:30 | | Optimal dilutions to be determined by the researcher. | | Positive Control | SKBr-3 cell lysates | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG | | Clone No | 9i45 | | Host | Rabbit | | Source | Human | | Concentration | Not determined | | Form | Supplied as a liquid in Tris-Glycine, pH 7.4, 0.15M sodium chloride, 0.05% BSA, 0.01% sodium azide, 40% glycerol. | | Purity | Supernatant | | Immunogen | Synthetic peptide corresponding to residues on human MMP-1. Cellular Localization: Secreted › extracellular space › extracellular matrix. | | Specificity | Recognizes human MMP-1. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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