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You are here:Home » Antibodies » Antibodies-Matrix Metalloproteinases » Anti -MMP2 (72kD Type IV Collagenase, 72kD Gelatinase, Matrix Metalloproteinase-2, MMP-2, Gelatinase A, TBE-1, CLG4A)

Anti -MMP2 (72kD Type IV Collagenase, 72kD Gelatinase, Matrix Metalloproteinase-2, MMP-2,
Gelatinase A, TBE-1, CLG4A)


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Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IH
Matrix metalloproteinase-2 (MMP2) is a Type IV collagenase, 72kD, which is also known as gelatinase and is a member of a group of secreted zinc metalloproteases. The MMP2 gene is 17kb long with 13 exons varying in size from 110-901bp and 12 introns ranging from 175 to 4,350bp 3, located within a region of human chromosome 16q13. In addition,The extra exons encode the aa of the fibronectin-like domain which has so far been found in only the 72-92kD type IV collagenase. MMP2, which has a critical role in the binding of progelatinase A and TIMP4 via the C-terminal hemopexin-like domain (C domain), is functionally associated on the surface of angiogenic blood vessels. NOT only is a likely effector of endometrial menstrual breakdown, MMP2 is also effector and regulator of the inflammatory response. Moreover, MMP2 could be helpful in diagnosing Takayasu arteritis.
Catalog #M2420-53D
ApplicationsSuitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 5-10ug/ml
Immunohistochemistry (Formalin fixed paraffin embedded): 20ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
FormSupplied as a liquid in 10mM PBS, pH 7.4, 0.2% BSA, 0.09% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenSynthetic peptide corresponding to second half of human MMP-2.
SpecificityRecognizes human MMP-2. Species sequence homology: Bovine, mouse, rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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