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You are here:Home » Antibodies » Abs to Matrix Metalloproteinases » Anti -MMP-2, ID (72kD Type IV Collagenase, 72kD Gelatinase, Gelatinase A, Matrix Metalloproteinase-2, TBE-1, MMP2, CLG4A)

Anti -MMP-2, ID (72kD Type IV Collagenase, 72kD Gelatinase, Gelatinase A, Matrix
Metalloproteinase-2, TBE-1, MMP2, CLG4A)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B IH
Matrix metalloproteinases (MMPs), also called matrixins, belong to a family of proteases that are essential for the breakdown of extracellular matrix (ECM). They are thus important in apoptosis, tumor cell growth, invasion, and metastasis as well as angiogenesis and wound healing. Most of the MMPs contain common domain structures that include a signal sequence, a propeptide, a catalytic domain, and a hemopexin-like (Hpx) domain. MMP-2 and MMP-9, the two gelatinases, contain three additional repeats of a fibronectin type II-like domain, enabling them to bind to and break down collagens. Studies on the zebrafish model have illuminated the function of MMP-2 on the remodeling, fin regeneration, and gastrulation.
Catalog #M2420-59A
ApplicationsSuitable for use in Western Blot, ELISA and Immunohistochemistry. Other applications not tested.
Recommended DilutionsELISA: 1:5000-1:20,000
Western Blot: 1:500-1:1000
Immunohistochemistry: 1:50-1:200
Optimal dilutions to be determined by the researcher.
Control Peptide M2420-59B
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceZebrafish
ConcentrationNot Determined
FormSupplied as a liquid in 40mM MOPS, pH 7.5, 0.1% BSA, 50% glycerol
PurityPurified by immunoaffinity chromatography
ImmunogenSynthetic peptide corresponding to the intermediate region of zebrafish MMP-2 (NP_932333).
SpecificityRecognizes zebrafish MMP-2.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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