Anti -MMP-3 (Stromelysin-1, SL-1, Matrix Metalloproteinase-3, Transin-1, MMP3, STMY1)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
B IH IF |
|
| Matrix metalloproteinases (MMP) are proteolytic enzymes capable of degrading connective tissue components. Imbalanced secretion of certain MMP or disturbances in the differential control of MMP by tissue inhibitor MMPs (TIMPs), implicated the invasive potential of malignant tumors. Stromelysin (MMP3 / Transin) degrades several matrix components including the core proteins of proteoglycans, laminin and non-helical regions of collagens. | | | Catalog # | M2421-10A | | Applications | Suitable for use in Immunofluorescence, Western Blot and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Immunohistochemistry: 1:10 for 60 min at RT | | Western Blot: 0.5-1ug/ml for 2hr, RT | | Optimal dilutions to be determined by the researcher. | | Positive Control | Conditioned, serum-free medium from TPA treated human endometrial cells, placenta, bladder, breast, ovarian carcinomas | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG2b,k | | Clone No | 2D3 | | Host | Mouse | | Source | Human | | Concentration | ~0.1mg/ml | | Form | Supplied as a liquid in PBS, pH 7.4, 0.2% BSA, 0.05% sodium azide. | | Purity | Purified by Protein A affinity chromatography. | | Immunogen | APMA activated human stromelysin-1 | | Specificity | Recognizes human MMP-3. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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