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You are here:Home » Antibodies » Abs to Matrix Metalloproteinases » Anti -MMP-3 (Stromelysin-1, SL-1, Matrix Metalloproteinase-3, Transin-1, MMP3, STMY1)

Anti -MMP-3 (Stromelysin-1, SL-1, Matrix Metalloproteinase-3, Transin-1, MMP3, STMY1)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified B IH IF
Matrix metalloproteinases (MMP) are proteolytic enzymes capable of degrading connective tissue components. Imbalanced secretion of certain MMP or disturbances in the differential control of MMP by tissue inhibitor MMPs (TIMPs), implicated the invasive potential of malignant tumors. Stromelysin (MMP3 / Transin) degrades several matrix components including the core proteins of proteoglycans, laminin and non-helical regions of collagens.
Catalog #M2421-10A
ApplicationsSuitable for use in Immunofluorescence, Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry: 1:10 for 60 min at RT
Western Blot: 0.5-1ug/ml for 2hr, RT
Optimal dilutions to be determined by the researcher.
Positive ControlConditioned, serum-free medium from TPA treated human endometrial cells, placenta, bladder, breast, ovarian carcinomas
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2b,k
Clone No2D3
HostMouse
SourceHuman
Concentration~0.1mg/ml
FormSupplied as a liquid in PBS, pH 7.4, 0.2% BSA, 0.05% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenAPMA activated human stromelysin-1
SpecificityRecognizes human MMP-3.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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