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You are here:Home » Antibodies » Abs to Matrix Metalloproteinases » Anti -MMP3 (Stromelysin-1, SL-1, Matrix Metalloproteinase-3, MMP-3, Transin-1, STMY1)

Anti -MMP3 (Stromelysin-1, SL-1, Matrix Metalloproteinase-3, MMP-3, Transin-1, STMY1)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Purified E IH
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP3 is an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation.
Catalog #M2421-15F
ApplicationsSuitable for use in ELISA and Immunohistochemistry. Other applications not tested.
Recommended DilutionELISA: 1:3000-1:8000
Immunohistochemistry (Frozen, Formalin fixed paraffin embedded): 2-5ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2a
Clone No11H57
HostMouse
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in 100mM Borate buffered saline, pH 8.2.
PurityPurified by ammonium sulfate precipitation.
ImmunogenRecombinant corresponding to human MMP-3.
SpecificityRecognizes human MMP-3. Does not react with human MMP-1, MMP-2 or MMP-9.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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