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You are here:Home » Antibodies » Abs to Matrix Metalloproteinases » Anti -MMP-7 (Matrilysin, Matrin, Matrix Metalloproteinase-7, MMP7, Pump-1 Protease, Uterine Metalloproteinase, MPSL1, PUMP1)

Anti -MMP-7 (Matrilysin, Matrin, Matrix Metalloproteinase-7, MMP7, Pump-1 Protease,
Uterine Metalloproteinase, MPSL1, PUMP1)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified IH IF
Matrix metalloproteinases (MMP) are proteolytic enzymes capable of degrading connective tissue components. Imbalanced secretion of certain MMP or disturbances in the differential control of MMP by tissue inhibitor of MMPs (TIMPs), implicated the invasive potential of malignant tumors. The matrix metalloproteinase, matrilysin / MMP-7 / PUMP-1, is thought to play an important role in the early steps of tumor progression. Expression of MMP2, -7, and -11 is greater in pancreatic carcinoma than in normal pancreas.
Catalog #M2423-21L
ApplicationsSuitable for use in Immunohistochemistry and Immunofluorescence. Other applications not tested.
Recommended DilutionImmunohistochemistry (Formalin fixed paraffin embedded): 1:25 for 30min at RT
Optimal dilutions to be determined by the researcher.
Positive ControlConditioned, serum-free medium from TPA treated human endometrial cells, placenta, bladder, breast, ovarian carcinomas
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2b,k
Clone No2D4
HostMouse
SourceHuman
Concentration~0.1mg/ml
FormSupplied as a liquid in PBS, pH 7.4, 0.2% BSA, 0.05% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenRecombinant corresponding to human matrilysin.
SpecificityRecognizes human MMP-7.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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