Anti -Matrix Metalloproteinase 9 (MMP-9, MMP9, 92kD Gelatinase, 92kD Type IV Collagenase,
Collagenase Type 4 beta, CLG4B, Collagenase Type IV 92kD, Collagenase 4, EC 3.4.24.35,
Gelatinase 92kD, Gelatinase B, Gelatinase beta, GELB, Macrophage Gelatinase, Type V
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Purified |
B IP IH |
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| MMPs are a group of enzymes involved in matrix degradation. They share some important characteristics, such as a common mode of activation, a conserved amino acid sequence in the putative metal binding-active site region, and specific proteinase inhibitors known as tissue inhibitors of metalloproteinases (TIMPs). Reportedly, MMPs play a crucial role in tumor cell invasion and metastasis. | | | Catalog # | M2425-02A | | Applications | Suitable for use in Western Blot, Immunohistochemistry and Immunoprecipitation. Other applications not tested. | | Recommended Dilutions | Immunoprecipitation: 2ug/mg | | Western Blot: 1-2ug/ml. Under non-reducing conditins only. | | Immunohistochemistry: Frozen | | Optimal dilutions to be determined by the researcher. | | Positive Controls | Conditioned, serum-free medium from (TPA-treated) human fibrosarcoma HT-1080 cells or CCL4 cells. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1,k | | Clone No | 8L694 | | Host | Mouse | | Source | Human | | Concentration | ~0.2mg/ml | | Form | Supplied as a liquid in PBS, pH 7.4, 0.2%BSA, 0.09% sodium azide | | Purity | Purified | | Immunogen | Full length human native 92kDa MMP-9 protein. Cellular Localization: Secreted | | Specificity | Recognizes pro (latent) and active forms of HUMAN MMP-9. Also reacts with the complex (~200kDa) of MMP-9 and tissue inhibitor of metalloproteinases-1 (TIMP-1). By Western Blot, a band at 92kDa (pro form) and ~86kDa (active form) which corresponds to the predicted molecular weight of MMP-9 is seen. No crossreaction with pro and active forms of MMP-2. Species Crossreactivity: rat. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Anti -Matrix Metalloproteinase 9 (MMP-9, MMP9, 92kD Gelatinase, 92kD Type IV Collagenase, Collagenase Type 4 beta, CLG4B, Collagenase Type IV 92kD, Collagenase 4, EC 3.4.24.35, Gelatinase 92kD, Gelatinase B, Gelatinase beta, GELB, Macrophage Gelatinase, Type V |
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