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You are here:Home » Antibodies » Abs to Matrix Metalloproteinases » Anti -MMP9, CT (Matrix Metalloproteinase-9, MMP-9, 92kD type IV Collagenase, 92kD Gelatinase, Gelatinase B, GELB, CLG4B)

Anti -MMP9, CT (Matrix Metalloproteinase-9, MMP-9, 92kD type IV Collagenase, 92kD
Gelatinase, Gelatinase B, GELB, CLG4B)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Purified E B IH
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP9 degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling.
Catalog #M2425-02B
ApplicationsSuitable for use in ELISA, Western Blot, and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 1:1000
Immunohistochemistry: 1:50-1:100
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, 0.09% sodium azide.
PurityPurified by ammonium sulfate precipitation.
ImmunogenKLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 644-673 in the C-terminal region of human MMP9, UniProt Accession #P14780
SpecificityRecognizes human MMP9. Species crossreactivity: mouse
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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