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You are here:Home » Antibodies » Abs to Matrix Metalloproteinases » Anti -MMP9 (Matrix Metalloproteinase-9, MMP-9, 92kD type IV Collagenase, 92kD Gelatinase, Gelatinase B, GELB, CLG4B)

Anti -MMP9 (Matrix Metalloproteinase-9, MMP-9, 92kD type IV Collagenase, 92kD Gelatinase,
Gelatinase B, GELB, CLG4B)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified B IH
Matrix metalloproteinases (MMPs) are zinc-dependent endopeptidases that degrade substances within the extracellular matrix. The MMP family includes six different groups of enzymes: collagenases, gelatinases, stromelysins, transmembrane MMPs, matrilysins and others. MMPs are secreted as proenzymes that have to be cleaved in order to be activated. Other MMPs, plasmins as well as other factors activate MMPs. MMPs are thought to play an important role in tissue remodeling associated with various physiological and pathological processes. MMP9 degrades of proteins in the extracellular matrix and activates growth factors like proTGFb and proTNFa. MMP-9 contributes to the invasion and metastasis of various human malignancies.
Catalog #M2425-28D
ApplicationsSuitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 5-10ug/5ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1,k
HostMouse
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide KLGLGADVAQVT conjugated to Ovalbumin.
SpecificityRecognizes human MMP9.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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