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You are here:Home » Antibodies » Abs to Matrix Metalloproteinases » Anti -MMP-10 (Stromelysin-2, SL-2, Matrix Metalloproteinase-10, Transin-2, MMP10, STMY2)

Anti -MMP-10 (Stromelysin-2, SL-2, Matrix Metalloproteinase-10, Transin-2, MMP10, STMY2)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified B IP IH
Matrix metalloproteinases (MMP) are proteolytic enzymes capable of degrading extracellular matrix. Stromelysin, a member of the matrix metalloproteinase family, demonstrates wide substrate specificity with the ability to degrade proteoglycan, fibronectin, laminin, casein, and nonhelical region of collagen. The two forms of stromelysin (SL), types 1 (MMP-3) and 2 (MMP-10), share 82% sequence homology, but exhibit differences in cellular synthesis and inducibility by cytokines and growth factors in vitro. This antibody recognizes pro (latent) and active forms of MMP-10.
Catalog #M2426-13J
ApplicationsSuitable for use in Immunoprecipitation, Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunoprecipitation: 2ug/mg protein lysate
Western Blot: 1-2ug/ml for 2h, room temperature
Immunohistochemistry: 1:50 for 30 min at RT
Optimal dilutions to be determined by the researcher.
Positive ControlConditioned, serum-free medium from (TPA-treated) human large cell lymphoma U937 cells, placenta, bladder, breast, ovarian carcinomas.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2b
Clone NoSPM345
HostMouse
SourceHuman
Concentration~0.1mg/ml
FormSupplied as a liquid in PBS, pH 7.4, 0.2% BSA, 0.05% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenRecombinant corresponding to human MMP-10.
SpecificityRecognizes human MMP-10.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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