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Abs to Matrix Metalloproteinases
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Anti -Matrix Metalloproteinase 10 (Matrix Metallopeptidase 10 (Stromelysin 2), Matrix Metalloproteinase-10, MMP10, MMP-10, Stromelysin-2, SL-2, STMY2, Transin-2)
Anti -Matrix Metalloproteinase 10 (Matrix Metallopeptidase 10 (Stromelysin 2), Matrix
Metalloproteinase-10, MMP10, MMP-10, Stromelysin-2, SL-2, STMY2, Transin-2)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Serum |
IH |
|
| Matrix metalloproteinases constitute a family of enzymes that exhibit a high affinity and lytic activity for a variety of extracellular matrix components, including collagens, proteoglycans, elastin, laminin, and fibronectin. They have an important role in processing enzymes that regulate cellular behavior and function by selective proteolysis of cell surface receptors and adhesion molecules, cytokines, and growth factors. The MMP-10 gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. It is recognized as collagenase-related connective tissue-degrading metalloproteinases capable of degrading multiple components of the extracellular matrix, or stroma. The enzyme encoded by this gene degrades proteoglycans and fibronectin. Its expression in normal Human tissues has been reported in T cells. Its pathological role has been observed in thymic lymphoma. | | | Catalog # | M2426-13K | | Applications | Suitable for use in Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Immunohistochemistry (paraffin): 1:25-1:50 | | Optimal dilutions to be determined by the researcher. | | Positive Control | Placenta | | Cellular Localization | | | Cytoplasmic | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | Not determined | | Form | Supplied as a liquid in 0.05% sodium azide. | | Purity | Serum | | Immunogen | Synthetic peptide from the hinge domain of human MMP-10. | | Specificity | Recognizes human MMP-10. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | EC=3.4.24.22 |
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