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You are here:Home » Antibodies » Abs to Matrix Metalloproteinases » Anti -MMP-11a, ID (Matrix Metallopeptidase 11A)

Anti -MMP-11a, ID (Matrix Metallopeptidase 11A)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B
Matrix Metalloproteinase 11a, a member of the matrix metalloproteinase family, demonstrates wide substrate specificity with the ability to degrade proteoglycan, fibronectin, laminin, casein, and the non-helical region of collagen. The MMP-11 gene was originally identified on the basis that it is expressed specifically in stromal cells surrounding invasive breast carcinomas. MMP-11 is a unique MMP because it is not secreted as a zymogen but is processed by furin within the constitutive secretory pathway. Compared with other MMPs, MMP-11 shows a different molecular structure, different activity, different gene organization and regulation. The MMP-11 was also studied in the Danio Rerio (zebrafish).
Catalog #M2427-14H
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:5000-1:20,000
Western Blot: 1:500-1:1000
Optimal dilutions to be determined by the researcher.
Control Peptide M2427-14R
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceZebrafish
ConcentrationNot determined
FormSupplied as a liquid in 40mM MOPS, pH 7.5, 0.1% BSA, 0.05% sodium azide, 50% glycerol.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to the intermediate region of zebrafish MMP-11a.
SpecificityRecognizes zebrafish MMP-11a.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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