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You are here:Home » Antibodies » Abs to Matrix Metalloproteinases » Anti -MMP-11 (Stromelysin-3, SL-3, ST3, Matrix Metalloproteinase-11, MMP11, STMY3)

Anti -MMP-11 (Stromelysin-3, SL-3, ST3, Matrix Metalloproteinase-11, MMP11, STMY3)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified B IP IH
Stromelysin, a member of the matrix metalloproteinase family, demonstrates wide substrate specificity with the ability to degrade proteoglycan, fibronectin, laminin, casein, and the nonhelical region of collagen. The stromelysin-3 (MMP-11) gene was originally identified on the basis that it is expressed specifically in stromal cells surrounding invasive breast carcinomas. MMP-11 is localized by in situ hybridization to the long arm of chromosome 22. The MMP-11 expression is found more specifically in malignant tumors than in benign ones.
Catalog #M2427-23B
ApplicationsSuitable for use in Immunoprecipitation, Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 1-2ug/ml for 2hr, room temperature
Immunoprecipitation: 2ug/mg protein lysate
Immunohistochemistry: 1:50 for 30 min at RT
Optimal dilutions to be determined by the researcher.
Positive ControlRecombinant MMP-11 protein, placenta.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1,k
Clone NoSPM199
HostMouse
SourceHuman
Concentration~0.1mg/ml
FormSupplied as a liquid in PBS, pH 7.4, 0.2% BSA, 0.05% sodium azide.
PurityPurified by Protein G affinity chromatography.
ImmunogenSemi-purified mitochondrial preparation
SpecificityRecognizes human MMP-11.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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