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Abs to Matrix Metalloproteinases
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Anti -MMP12 (Macrophage Metalloelastase, MME, Macrophage Elastase, ME, hME, Matrix Metalloproteinase-12, MMP-12, HME)
Anti -MMP12 (Macrophage Metalloelastase, MME, Macrophage Elastase, ME, hME, Matrix
Metalloproteinase-12, MMP-12, HME)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B IH |
|
| MMP12 is a Metallopeptidase M10A type protease. MMP-12 degrads extracellular matrix components such as elastin and is involved in tissue remodeling processes. MMP12 is a proteolytic enzyme responsible for cleavage of plasminogen to angiotensin. Studies using animal models of acute and chronic pulmonary inflammatory diseases, have given evidences that MMP-12 is an important mediator of the pathogenesis of these diseases. | | | Catalog # | M2427-60B | | Applications | Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in PBS, 0.02% thimerosal, 30% glycerol. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide corresponding to aa460 from human MMP-12. | | Specificity | Recognizes human MMP12. Species sequence homology: mouse. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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