You are here:Home
»
Antibodies
»
Abs to Matrix Metalloproteinases
»
Anti -MMP-13a, Hinge (Matrix Metalloproteinase 13, mmp13)
Anti -MMP-13a, Hinge (Matrix Metalloproteinase 13, mmp13)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
E B IH |
|
| The matrix metalloproteinases (MMPs) constitute a family of zinc- dependent endopeptidases that function within the extracellular matrix. These enzymes are responsible for the breakdown of connective tissues and are important in bone remodeling, menstrual cycle and the repair of tissue damage. MMP-13 (collagenase-3) is a member of the MMP family of extracellular proteases. Targets of MMP-13 include collagen, gelatin, aggracan, plasminogen and CXCL12. MMP-13 is secreted as a 60kD proenzyme (as measured by SDS-PAGE), and activated by cleavage to a mature 48kD MMP-13. MMP-13 is an important target for inhibitor screening due to its involvement in diseases such as cancer and arthritis. | | | Catalog # | M2428-09J | | Applications | Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | ELISA: 1:5000-1:20,000 | | Western Blot: 1:500-1:1000 | | Immunohistochemistry: 1:200 | | Optimal dilutions to be determined by the researcher. | | Control Peptide | M2428-09P | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Zebrafish | | Concentration | As reported | | Form | Supplied as a liquid in 40mM MOPS, pH 7.5, 0.1 % BSA, 0.05% sodium azide, 50% glycerol. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide corresponding to the hinge region of zebrafish MMP-13. | | Specificity | Recognizes zebrafish MMP-13. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
External Links
|
