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You are here:Home » Antibodies » Abs to Matrix Metalloproteinases » Anti -MMP17 (Matrix Metalloproteinase-17, MMP-17, Membrane-type Matrix Metalloproteinase 4, MT-MMP 4, MTMMP4, Membrane-type-4 Matrix Metalloproteinase, MT4-MMP, MT4MMP, MT4MMP)

Anti -MMP17 (Matrix Metalloproteinase-17, MMP-17, Membrane-type Matrix Metalloproteinase
4, MT-MMP 4, MTMMP4, Membrane-type-4 Matrix Metalloproteinase, MT4-MMP, MT4MMP, MT4MMP)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E IH
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP17 is considered a member of the membrane-type MMP (MT-MMP) subfamily. However, this protein is unique among the MT-MMPs in that it is a GPI-anchored protein rather than a transmembrane protein. The protein activates MMP-2 by cleavage.
Catalog #M2432-01B
ApplicationsSuitable for use in ELISA and Immunohistochemistry. Other applications not tested.
Recommended DilutionELISA: 1:1000
Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostRabbit
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, 0.1% sodium azide.
PurityPurified by Protein G affinity chromatography.
ImmunogenSynthetic peptide corresponding to aa409-423 of human MMP17 (KLH).
SpecificityRecognizes human MMP17.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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