Anti -MMP23, NT (Matrix Metalloproteinase-23, MMP-23, Matrix Metalloproteinase-21, MMP-21,
Matrix Metalloproteinase-22, MMP-22, Femalysin, MIFR-1, MMP23A, MMP21, MMP23B, MMP21,
MMP22)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
E B |
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| Matrix Metalloproteases (MMPs) are zinc-dependent endopeptidases that break down the extracellular matrix, and thus play important roles in many physiological processes including embryonic development, wound healing, reproduction, tissue remodeling, arthritis, cancer and cardiovascular disease. Although most MMPs are secreted, the membrane-type MMPs (MT-MMPs) are anchored to the cell membrane by a transmembrane and intracytoplasmic domain. MMP activities are regulated at several levels, including cleavage of proenzyme forms and suppression via tissue inhibitors of metalloproteinases (TIMPs). Matrix Metalloproteinase 23, first identified in tumor cells, features a number of unqie properties among the MMPs: 1) cysteine array unique among the MMPs, 2) sublocalized expression of MMP23 to reproductive organs, 3) a furin cleavage site, 4) and is the sole MMP mapped to chromosome 1. | | | Catalog # | M2436-02A | | Applications | Suitable for use in ELISA and Western Blot. Other applications not tested. | | Recommended Dilution | ELISA: 1:1,000 | | Western Blot: 1:100-1:500 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | ~0.25mg/ml | | Form | Supplied as a liquid in PBS, 0.09% sodium azide. | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | Synthetic peptide selected from the N-terminal region of human MMP23 (KLH). | | Specificity | Recognizes human MMP23. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Anti -MMP23, NT (Matrix Metalloproteinase-23, MMP-23, Matrix Metalloproteinase-21, MMP-21, Matrix Metalloproteinase-22, MMP-22, Femalysin, MIFR-1, MMP23A, MMP21, MMP23B, MMP21, MMP22) |
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