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You are here:Home » Antibodies » Abs to Matrix Metalloproteinases » Anti -MMP24, ID (Matrix Metalloproteinase-24, MMP-24, Membrane-type Matrix Metalloproteinase 5, MT-MMP 5, MTMMP5, Membrane-type-5 Matrix Metalloproteinase, MT5-MMP, MT5MMP, MT5MMP)

Anti -MMP24, ID (Matrix Metalloproteinase-24, MMP-24, Membrane-type Matrix
Metalloproteinase 5, MT-MMP 5, MTMMP5, Membrane-type-5 Matrix Metalloproteinase, MT5-MMP,
MT5MMP, MT5MMP)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B IH
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, MMP24 is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 by cleavage. The gene has previously been referred to as MMP25 but has been renamed matrix metalloproteinase 24 (MMP24).
Catalog #M2436-04
ApplicationsSuitable for use in ELISA, Western Blot, and Immunohistochemistry. Other applications not tested.
Recommended DilutionELISA: 1:1,000
Western Blot: 1:100-1:500
Immunohistochemistry: 1:50-1:100
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, 0.09% sodium azide.
PurityPurified by Protein G affinity chromatography.
ImmunogenSynthetic peptide selected from the center region of human MMP24 (KLH).
SpecificityRecognizes human MMP24.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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