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You are here:Home » Antibodies » Abs to Matrix Metalloproteinases » Anti -MMP25, CT (Matrix Metalloproteinase-25, MMP-25, Membrane-type Matrix Metalloproteinase 6, MT-MMP 6, MTMMP6, Membrane-type-6 Matrix Metalloproteinase, MT6-MMP, MT6MMP, Leukolysin, MMP20, MMPL1, MT6MMP)

Anti -MMP25, CT (Matrix Metalloproteinase-25, MMP-25, Membrane-type Matrix
Metalloproteinase 6, MT-MMP 6, MTMMP6, Membrane-type-6 Matrix Metalloproteinase, MT6-MMP,
MT6MMP, Leukolysin, MMP20, MMPL1, MT6MMP)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B FC
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, MMP25 is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. In addition, it is thought that this protein is activated intracellularly by furin-like enzymes. This protein activates MMP2 by cleavage. The gene has previously been referred to as MMP20 but has been renamed matrix metalloproteinase 25 (MMP25).
Catalog #M2438-10A
ApplicationsSuitable for use in ELISA, Western Blot, and Flow Cytometry. Other applications not tested.
Recommended DilutionWestern Blot: 1:100-1:500
ELISA: 1:1,000
Flow Cytometry: 1:10-1:50
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, 0.09% sodium azide.
PurityPurified by Protein G affinity chromatography.
ImmunogenSynthetic peptide selected from the C-terminal region of human MMP25 (KLH).
SpecificityRecognizes human MMP25. Species Crossreactivity: mouse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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