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You are here:Home » Antibodies » Antibodies-Matrix Metalloproteinases » Anti -MMP27, CT (Matrix Metalloproteinase-27, MMP-27, UNQ2503/PRO5992)

Anti -MMP27, CT (Matrix Metalloproteinase-27, MMP-27, UNQ2503/PRO5992)


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Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E IH
Matrix Metalloproteases (MMPs) are zinc-dependent endopeptidases that break down the extracellular matrix, and thus play important roles in many physiological processes including embryonic development, wound healing, reproduction, tissue remodeling, arthritis, cancer and cardiovascular disease. Although most MMPs are secreted, the membrane-type MMPs (MT-MMPs) are anchored to the cell membrane by a transmembrane and intracytoplasmic domain. MMP activities are regulated at several levels, including cleavage of proenzyme forms and suppression via tissue inhibitors of metalloproteinases (TIMPs). The 513aa human MMP27 protein is located primarily in extracellular spaces in the extracellular matrix, and maps to chromosome 11q24.
Catalog #M2438-17A
ApplicationsSuitable for use in ELISA and Immunohistochemistry. Other applications not tested.
Recommended DilutionELISA: 1:1000
Immunohistochemistry (Formalin fixed paraffin embedded): 10ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
FormSupplied as a liquid in PBS, 0.1% sodium azide.
PurityPurified by Protein G affinity chromatography.
ImmunogenSynthetic peptide corresponding to aa445-459 of human MMP27 (KLH).
SpecificityRecognizes human MMP27.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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