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You are here:Home » Antibodies » Abs to Matrix Metalloproteinases » Anti -MMP28, Hinge (Matrix Metalloproteinase-28, MMP-28, Epilysin, MMP25, UNQ1893/PRO4339)

Anti -MMP28, Hinge (Matrix Metalloproteinase-28, MMP-28, Epilysin, MMP25, UNQ1893/PRO4339)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B IH
Matrix metalloproteinases (MMPs), also called matrixins, belong to a family of proteases that are essential for the breakdown of extracellular matrix (ECM). They are thus important in apoptosis, tumor cell growth, invasion, and metastasis as well as angiogenesis and wound healing. Most of the MMPs contain common domain structures that include a signal sequence, a propeptide, a catalytic domain, and a hemopexin-like (Hpx) domain. MMP-28, also named epilysin, is expressed in many tissues such as lung, placenta, heart, gastrointestinal tract and testis. The enzyme expressed in basal keratinocytes in skin is considered to function in wound repair. It is also elevated in cartilage from patients with osteoarthritis and rheumatoid arthritis.
Catalog #M2438-19
ApplicationsSuitable for use in Western Blot, ELISA and Immunohistochemistry. Other applications not tested.
Recommended DilutionELISA: 1:5000-1:20,000
Western Blot: 1:500-1:1000
Immunohistochemistry: 1:50-1:200
Optimal dilutions to be determined by the researcher.
Control Peptide M2438-19P
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceZebrafish
ConcentrationNot determined
FormSupplied as a liquid in 40mM MOPS, pH 7.5, 0.1 % BSA, 0.05% sodium azide, 50% glycerol.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to the hinge region of zebrafish MMP-28.
SpecificityRecognizes zebrafish MMP-28.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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