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Anti -Matrix Metalloproteinase MT1 (MT1 MMP, Membrane Type 1, MMP-14)
Anti -Matrix Metalloproteinase MT1 (MT1 MMP, Membrane Type 1, MMP-14)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Purified |
E B IH |
|
| Matrix metalloproteinases (MMPs) are Zn 2+ and Ca 2+-dependent endopeptidases which function in the turnover of extracellular matrix components. Presently, eighteen secreted MMPs and five membrane-type MMPs (2–5) are known to be expressed in vertebrates. Human MT1-MMP consists of 559 amino acid residues with a calculated Mr of 63516. | | | Catalog # | M2441-01 | | Applications | Suitable for use in Western Blot, Immunohistochemistry and ELISA. Other applications not tested. | | Recommended Dilutions | Western Blot: 8-20ug/ml | | Immunohistochemistry (Paraffin): 20ug/ml. Requires periodate-lysine-paraformaldehyde for 18-24 hours at 4ºC. | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1,k | | Clone No | 2Q527 | | Host | Mouse | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in PBS, pH 7.0, 2% BSA (protease free). | | Purity | Purified | | Immunogen | Peptide corresponding to aa160-173, REVPYAYIREGHEK of human membrane-type 1 matrix metalloproteinase. | | Specificity | Recognizes human MT1-MMP. For unknown reasons this antibody does not react on Westerns to Cat# M2429-06. Does not crossreact with mouse, rat or porcine. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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