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You are here:Home » Antibodies » Antibodies-Matrix Metalloproteinases » Anti -Matrix Metalloproteinase MT1 (MT1 MMP, Membrane Type 1, MMP-14)

Anti -Matrix Metalloproteinase MT1 (MT1 MMP, Membrane Type 1, MMP-14)


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Clone Host Grade Applications
Monoclonal Mouse Purified E B IH
Matrix metalloproteinases (MMPs) are Zn 2+ and Ca 2+-dependent endopeptidases which function in the turnover of extracellular matrix components. Presently, eighteen secreted MMPs and five membrane-type MMPs (25) are known to be expressed in vertebrates. Human MT1-MMP consists of 559 amino acid residues with a calculated Mr of 63516.
Catalog #M2441-01
ApplicationsSuitable for use in Western Blot, Immunohistochemistry and ELISA. Other applications not tested.
Recommended DilutionsWestern Blot: 8-20ug/ml
Immunohistochemistry (Paraffin): 20ug/ml. Requires periodate-lysine-paraformaldehyde for 18-24 hours at 4ºC.
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. 
Clone TypeMonoclonal
Clone No2Q527
FormSupplied as a liquid in PBS, pH 7.0, 2% BSA (protease free).
ImmunogenPeptide corresponding to aa160-173, REVPYAYIREGHEK of human membrane-type 1 matrix metalloproteinase.
SpecificityRecognizes human MT1-MMP. For unknown reasons this antibody does not react on Westerns to Cat# M2429-06. Does not crossreact with mouse, rat or porcine.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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