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You are here:Home » Antibodies » Abs to Binding Proteins » Anti -MBD2a (Methyl CpG Binding Domain Protein 2a, Demethylase, DMTase, DKFZp586O0821, MBD2, Methyl CpG Binding Domain Protein 2 Isoform 1, Methyl CpG Binding Protein MBD2, NY-CO-41)

Anti -MBD2a (Methyl CpG Binding Domain Protein 2a, Demethylase, DMTase, DKFZp586O0821,
MBD2, Methyl CpG Binding Domain Protein 2 Isoform 1, Methyl CpG Binding Protein MBD2,
NY-CO-41)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
The MBD family of proteins includes MeCP2, MBD1, MBD2, MBD3 and MBD4. MBD2 is highly similar to MBD3 but only MBD2 targets the MeCP1 complex to methylate DNA. MBD2 has two isoforms, MBD2a and MBD2b. MBD2a is a 414aa protein, whereas MBD2b lacks the 152aa N-terminal extension. MBD2a interacts with RNA helicase A to enhance CREB-dependent gene exptression.
Catalog #M2472-01A
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 0.5-4ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceRat
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, pH 7.2, 0.5% BSA, 5mM EDTA, 0.01% thimerosal, 30% glycerol.
PurityPurified by affinity chromatography.
ImmunogenSynthetic peptide corresponding to aa164 from rat MBD2a.
SpecificityRecognizes rat MBD2a. Species Crossreactivity: human and mouse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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