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Anti -MCAF (MBD1-containing Chromatin Associated Factor, MCAF1, Activating Transcription Factor 7 Interacting Protein 1, ATF7IP, ATF Interacting Protein, ATF-IP, ATFa-associated Modulator, hAM, p621)
Anti -MCAF (MBD1-containing Chromatin Associated Factor, MCAF1, Activating Transcription
Factor 7 Interacting Protein 1, ATF7IP, ATF Interacting Protein, ATF-IP, ATFa-associated
Modulator, hAM, p621)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B IP IH |
|
| MBD1-containing chromatin-associated factor (MCAF) is a 1270-residue mediator in the DNA methylation cycle of a variety of genomic functions. This nuclear protein will bind to the C-terminal transcriptional repression domain of MBD1 to form a blocking complex. This molecule will then prevent transcription from methylated promoters in a histone deacetylation-independent action. | | | Catalog # | M2690-19B | | Applications | Suitable for use in Western Blot, Immunoprecipitation and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Western Blot: 1:5000-1:20,000 | | Optimal dilutions to be determined by the researcher. | | Positive Control | HeLa Nuclear Extract | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | N/A | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid, 0.1% sodium azide | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide corresponding to aa25-100 of human MBD1-containing Chromatin Associated Factor (AAQ92978.1)(GeneID 55729). | | Specificity | Recognizes human MBD1-containing Chromatin Associated Factor. Species sequence homology: mouse based upon conservation between this ortholog and human MCAF at the site to which the epitope maps. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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