Anti -MCM2 (Mini Chromosome Maintenance Protein 2, MCM2 Minichromosomal Maintenance
Deficient 2 Mitotin, BM28, Cyclin-like 1, CCNL1, Cell Devision Cycle-like 1, CDC like-1,
CDCL1, cdc19, D3S3194, DNA Replication Licensing Factor MCM2, KIAA0030, MGC10606, Mitoti
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B IP |
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| MCM2 (mini chromosome maintenance protein 2) is a putative DNA replicative helicase and member of the MCM family, critical during the initiation of DNA replication. | | | During the G1 phase of the cell cycle the MCM proteins, part of the pre-replicative complex which assembles at replication origins, undergo phosphorylation by kinases including cyclin dependent kinase (CDK) and Cdc7/Dbf4 (DDK). Studies have shown that the phosphorylation of MCM2 occurs on multiple sites, namely Ser27, Ser41, Ser53, Ser108 and Ser139 and that phosphorylation results in a conformational change of the complex and activation of the helicase activity. | | | Catalog # | M2749-29 | | Applications | Suitable for use in Immunoprecipitation and Western Blot. Other applications not tested. | | Recommended Dilution | Immunoprecipitation: 2-5ug/mg lysate | | Western Blot: 1:1,000-1:10,000. Detects a band of approximately 120-130kD in HeLa RIPA extracts. | | Optimal dilutions to be determined by the researcher. | | Control Peptide | See M2749-29A | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in Tris-citrate/phosphate, 0.09% sodium azide. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide corresponding to an epitope within amino acid residues 1-50 of human MCM2 (NP_004517.2). | | Specificity | Recognizes human MCM2 (mini chromosome maintenance protein 2) nuclear protein. Species Crossreactivity: Xenopus. Expected to crossreact with mouse based on sequence homology. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Anti -MCM2 (Mini Chromosome Maintenance Protein 2, MCM2 Minichromosomal Maintenance Deficient 2 Mitotin, BM28, Cyclin-like 1, CCNL1, Cell Devision Cycle-like 1, CDC like-1, CDCL1, cdc19, D3S3194, DNA Replication Licensing Factor MCM2, KIAA0030, MGC10606, Mitoti |
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