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You are here:Home » Antibodies » Abs to DNA Replication, Repair » Anti -MCM2, phosphorylated (Ser53) (Mini Chromosome Maintenance Protein 2, MCM2 Minichromosomal Maintenance Deficient 2 Mitotin, BM28, Cyclin-like 1, CCNL1, Cell Devision Cycle-like 1, CDC like-1, CDCL1, cdc19, D3S3194, DNA Replication Licensing Factor MCM2, KI

Anti -MCM2, phosphorylated (Ser53) (Mini Chromosome Maintenance Protein 2, MCM2
Minichromosomal Maintenance Deficient 2 Mitotin, BM28, Cyclin-like 1, CCNL1, Cell Devision
Cycle-like 1, CDC like-1, CDCL1, cdc19, D3S3194, DNA Replication Licensing Factor MCM2, KI

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7.
Catalog #M2749-30V
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot:1:1000-1:2500
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~0.2mg/ml
FormSupplied as a liquid in TBS, pH 7.2, 0.1% BSA, 0.09% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic phosphopeptide corresponding to a portion of human minichromosomal maintenance deficient 2 (MCM2) surrounding Ser53 (GeneID 4171).
SpecificityRecognizes human MCM2 when phosphorylated at Ser53.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesMinichromosome Maintenance Protein 2 Homolog


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