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You are here:Home » Antibodies » Abs to DNA Replication, Repair » Anti -MCM4 (Minichromosome Maintenance Deficient 4, CDC21, CDC21 Homolog, CDC54, DNA Replication Licensing Factor MCM4, hCdc21, Homolog of S. pombe Cell Devision Cycle 21, MGC33310, Minichromosome Maintenance 4, Minichromosome Maintenance Complex Component 4, P

Anti -MCM4 (Minichromosome Maintenance Deficient 4, CDC21, CDC21 Homolog, CDC54, DNA
Replication Licensing Factor MCM4, hCdc21, Homolog of S. pombe Cell Devision Cycle 21,
MGC33310, Minichromosome Maintenance 4, Minichromosome Maintenance Complex Component 4, P

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified B
MCM4 is involved in the initiation and control of eukaryotic DNA replication. Studies show that MCM4 forms a hexameric protein complex with MCM6 and 7, which has DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of MCM4 by CDC2 kinase reduces the DNA helicase activity and chromatin binding of the MCM complex.
Catalog #M2749-32G
This antibody can be blocked by the control peptide BLP041.
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1:2,000-1:10,000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in Tris-citrate/phosphate, pH 7.5, 0.09% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to a region within human MCM4 (locus link ID 4173)
SpecificityRecognizes human minichromosome maintenance deficient 4 (MCM4).
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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