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Abs to DNA Replication, Repair
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Anti -MCM6 (Minichromosome Maintenance Protein 6, DNA Replication Licensing Factor MCM6, MCG40308, Minichromosome Maintenance Deficient (mis5 S. pombe) 6, MIS5 Homolog, P105MCM)
Anti -MCM6 (Minichromosome Maintenance Protein 6, DNA Replication Licensing Factor MCM6,
MCG40308, Minichromosome Maintenance Deficient (mis5 S. pombe) 6, MIS5 Homolog, P105MCM)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B |
|
| MCM6 is involved in the initiation and control of eukaryotic DNA replication. Studies show that MCM4 forms a hexameric protein complex with MCM6 and 7, which has DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of this complex by CDC2 kinase reduces the DNA helicase activity and chromatin binding of the MCM complex. | | | Catalog # | M2749-36F | | This antibody can be blocked by the control peptide BLP043. | | Applications | Suitable for use in Western Blot. Other applications not tested. | | Recommended Dilution | Western Blot: 1:2,000-1:10,000 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in Tris-citrate/phosphate, pH 7.5, 0.09% sodium azide. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide corresponding to a region within human MCM6 (locus link ID 4175) | | Specificity | Recognizes human minichromosome maintenance deficient 6 (MCM6). | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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