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You are here:Home » Antibodies » Abs to DNA Replication, Repair » Anti -MCM7 (Minichromosome Maintenance Protein 7, CDABP0042, CDC47, CDC47 Homolog, DNA Replication Licensing Factor MCM7, Homolog of S. cerevisiae Cdc47, MCM7 Minichromosome Maintenance Deficient 7, Minichromosome Maintainence 7, P1.1-MCM3, P1CDC47, P85MCM, PNA

Anti -MCM7 (Minichromosome Maintenance Protein 7, CDABP0042, CDC47, CDC47 Homolog, DNA
Replication Licensing Factor MCM7, Homolog of S. cerevisiae Cdc47, MCM7 Minichromosome
Maintenance Deficient 7, Minichromosome Maintainence 7, P1.1-MCM3, P1CDC47, P85MCM, PNA

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B IH IF
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Catalog #M2749-37E
ApplicationsSuitable for use in ELISA, Immunofluorescence, Immunohistochemistry and Western Blot. Other applications not tested.
Recommended DilutionImmunohistochemistry (paraffin): 1.5ug/ml
Western Blot: 1:500-1:1000
ELISA: 1ug/ml-3ng/ml
Optimal dilutions to be determined by the researcher.
HybridomaSp2/0 myeloma cells with spleen cells from Balb/c mice.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG2a
Clone No10B2436
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2. No preservative added (Azide free).
PurityPurified by Protein A affinity chromatography.
ImmunogenRecombinant protein with a GST tag corresponding to aa1-390 of human MCM7.
SpecificityRecognizes human MCM7.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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