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You are here:Home » Antibodies » Abs to Ubiquitin » Anti -MDM2 (Murine Double Minute-2)

Anti -MDM2 (Murine Double Minute-2)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E IH
Catalog #M2800-07A
Human homolog of murine double minute-2 (MDM2) and p53 function in mutual regulation activation of p53 results in expression of MDM2, which consequently inhibits the ability of wild type p53 to stimulate expression of target genes. MDM2 is frequently overexpressed in the nuclei of soft tissue sarcomas, and to a much lesser extent in a wide variety of malignancies of bladder, breast, testes, cervix, glial cells.
ApplicationsSuitable for use in Immunohistochemistry. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. 
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~0.2mg/ml
FormSupplied as a liquid in 10mM PBS, pH 7.6, 0.2% BSA, 15mM sodium azide.
PurityPurified
ImmunogenSynthetic peptide corresponding to aa154-167 from human MDM2. Cellular Localization
SpecificityRecognizes human MDM2. Species Crossreactivity: mouse, rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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